Summary
Overview
Work History
Education
Skills
Achievements
Timeline
Generic

Yue Sun

Research Assistant
Shanghai

Summary

About me: I have studied tumor immunity for three years, and my main research is on the function improvement of U-CART. I have mastered experimental operation skills and have good literature reading and learning ability. In life, I have a cheerful personality and can adapt to new environments quickly.

Overview

5
5
years of professional experience
7
7
years of post-secondary education

Work History

High School Biology Teacher

Shanghai East Foreign Language School Affiliated T
08.2023 - Current
  • As a high school biology teacher, I teach students molecular biology, biochemistry, immunology and other related content.
  • Responsible for leading students to complete basic experimental operations.
  • Developed and implemented engaging lesson plans that aligned with curriculum standards, enhancing student understanding of biological concepts.

Intern

BRL Medicine Inc.
09.2020 - 06.2023
  • Company Overview: BRL Medicine Inc. is involved in cell therapy research and development.
  • As a member of the U-CART team, build and improve U-CART to enhance its functionality.

Education

Master's degree - Biochemistry & Molecule Biology

East China Normal University
09.2020 - 06.2023

Bachelor's degree - Life Science

Tonghua Normal University
09.2016 - 09.2020

Skills

  • Basic experimental skills in molecular biology:Plasmid design ,extraction, separation, purification and identification of nucleic acid substances, electrophoresis technology, primer design, PCR amplification, molecular markers, gene cloning, etc

  • Cell culture&Cell transfection and gene editing : plasmid transfection (electroporation), Viral vector (lentiviral packaging), CRISPR-Cas9 gene editing (sgRNA design, knockout/knockin verification)

  • Cell function detection:
    Cell proliferation/toxicity detection (MTT, CCK-8, EdU), Apoptosis detection (Annexin V-FITC/PI, TUNEL), Migration and invasion assay (Transwell, scratch assay)

Achievements

Publications:

1. Zhang N, Liu X, Qin J, Sun Y, Xiong H, Lin B, Liu K, Tan B, Zhang C, Huang C, Ren S, Liu M, Du B. LIGHT/TNFSF14 promotes CAR-T cell trafficking and cytotoxicity through reversing immunosuppressive tumor microenvironment. MolTher. 2023 Jul 5:S1525-0016(23)00372-6. doi: 10.1016/j.ymthe.2023.06.015. PMID: 37408308. (IF: 12.91)

2. Liu X, Sun Y, Lin B, Xiong H, Lu X, Tan B, Zhang C, Liu M, Qin J, Zhang N, Du B. Pan-cancer analysis identifies CD155 as a promising target for CAR-T cell therapy. Genome Med. 2025 Jun 2;17(1):64. doi: 10.1186/s13073-025-01490-0. PMID: 40457441; PMCID: PMC12128359. (IF: 10.4) co-first

3. Cui X, Xing R, Tian Y, Wang M, Sun Y, Xu Y, Yang Y, Zhao Y, Xie L, Xiao Y, Li D, Zheng B, Liu M, Chen H. The G2A Receptor Deficiency Aggravates Atherosclerosis in Rats by Regulating Macrophages and Lipid Metabolism. Front Physiol. 2021 Jul 26;12:659211. doi: 10.3389/fphys.2021.659211. PMID: 34381373; PMCID: PMC8351205. (IF: 3.287)

Patents:

4. Liu Xiaohong, Sun Yue, Du Bing, Tan Binghe, Zhang Na, Liu Mingyao, chimeric antigen receptor targeting immune cell activation receptor. PCT international patent (International application number: PCT/CN2023/135665)

Timeline

High School Biology Teacher

Shanghai East Foreign Language School Affiliated T
08.2023 - Current

Intern

BRL Medicine Inc.
09.2020 - 06.2023

Master's degree - Biochemistry & Molecule Biology

East China Normal University
09.2020 - 06.2023

Bachelor's degree - Life Science

Tonghua Normal University
09.2016 - 09.2020
Yue SunResearch Assistant