Summary
Work History
Education
Skills
Publications
Timeline
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QIN XU

QIN XU

Postdoc
Beijing, China

Summary

  • Seeking a full-time position that offers professional challenges that I can solve utilizing my chemistry skills, excellent time management, and problem-solving abilities.
  • My future role will benefit from my self-motivation and work ethic which were built up during my education and professional career.
  • Highly experienced in synthesis, drug discovery and development relating to drug targets, drug-protein interactions, structure-activity relationships, and drug-like property improvement.

Work History

Postdoctoral Research Associate

Tsinghua University
Beijing
05.2023 - 10.2023

• Designed and executed synthesis procedures for research projects in varying phases.
• Synthesized a novel proximity labeling probe based on iridium photo-catalyst, which enables discovery of potential drug targets.
• Leveraged interpersonal and communication skills to mentor PhD and undergraduate students.
• Contributed to and actively participated in research conception, design, and execution to address defined problems.
• Designed research projects and alternative approaches, then discussed the results with the professor.
• Collaborated with team members to accomplish biological research goals.
• Maintained accurate records of research findings and provided chemical characterization data.
• Enforced laboratory safety protocols and maintained safe work environment.
• Wrote and submitted two research grant applications for the benefit of the research team.
• Received the honorable title "Shuimu Scholar**" from Tsinghua University for personal academic excellence.

*Tsinghua University is a top-rated university in China. It was ranked 12th in World University Rankings 2024 by Times Higher Education.
**Shuimu Scholar is a competitive honor. I was the only one who won the honor in the School of Pharmacy and Pharmaceutical Sciences.

Education

Ph.D. - Pharmaceutical Sciences

Cardiff University
Wales, UK
10.2017 - 03.2022

Master of Science - Medicinal Chemistry

Cardiff University
Wales
10.2016 - 09.2017

Bachelor of Science - Pharmaceutical Sciences

Jiangxi University of Traditional Chinese Medicine
Jiangxi
07.2015

Skills

  • Small Molecule Drug Design and Development
  • Synthesis Plan from Scratch
  • Problem Solving and Synthesis Optimization
  • Proficient at Equipment for Chemistry such as NMR, MS, HPLC, etc
  • Familiar with Biological Assays such as Western Blots
  • Data Collection and Analysis
  • Strong Software Skills in Chemdraw, Mestrenova, Graphpad, ImageJ, etc
  • Academic Writing
  • Presentations and Discussions

Publications

  • Kadri, H., Taher, T. E., Xu, Q., Sharif, M., Ashby, E., Bryan R. T., Willcox, B. E*. and Mehellou, Y*. 2020. Aryloxy diester phosphonamidate prodrugs of phosphoantigens (ProPAgens) as potent activators of Vγ9/Vδ2 T-Cell immune responses. Journal of Medicinal Chemistry 63(19), pp. 11258-11270. (Equal contribution)


  • Xu, Q., Taher, T. E., Ashby, E., Sharif, M., Willcox, B. E*. and Mehellou, Y*. 2021. Generation of stable isopentenyl monophosphate aryloxy triester phosphoramidates as activators of Vγ9Vδ2 T cells. ChemMedChem 16(15), pp. 2375-2380


  • Xu, Q., Sharif, M., James, E., Dismorr, J., Tucker, J., Willcox, B. E*., Mehellou, Y*. 2023. Phosphonodiamidate Prodrugs of Phosphoantigens (ProPAgens) Exhibit Potent Vγ9/Vδ2 T Cell Activation and Eradication of Cancer Cells. Journal of Medicinal Chemistry. (Revised Manuscript Submitted).

Timeline

Postdoctoral Research Associate

Tsinghua University
05.2023 - 10.2023

Ph.D. - Pharmaceutical Sciences

Cardiff University
10.2017 - 03.2022

Master of Science - Medicinal Chemistry

Cardiff University
10.2016 - 09.2017

Bachelor of Science - Pharmaceutical Sciences

Jiangxi University of Traditional Chinese Medicine
QIN XUPostdoc